CURRENT ISSUE
Editorial
Turkish Journal of Immunology: Launching the 2025 Volume
Günnur Deniz
Dear Colleagues,
It is our great pleasure to present the first issue of the Turkish Journal of Immunology for 2025. This issue highlights the diversity and depth of current immunological research. In our Review Article, the emerging concept of PANoptosis is explored as a novel form of programmed (...)
Review Article
PANoptosis: A Coordinated Response in the Diversity of Cell Death
Mert Karaca
and Haluk Barbaros Oral
Programmed cell death (PCD) mechanisms are an inherent part of protection against pathogens and cellular stress. Pyroptosis, apoptosis, and necroptosis are the best-known PCD pathways that protect the body against both internal and external risk factors. The observation that all three cell death pathways can be activated in response to certain stimuli, such as influenza virus (IAV) infection, has raised the question of whether they are triggered independently or work in (...)
Original Research
Impact of Genetic Background and Gender on Mouse Susceptibility to H1N1- PR8: Implication of the Host Immune Responses
Mahmoud Mohamed Bahgat
Due to feasibility, small size, easiness of handling and maintaining in an animal house, uncomplicated ethical approval to work with, and a high degree of homology to both the human genome and metabolome (...)
and others
Validation and Comparative Analysis of Dihydrorhodamine 123 Oxidative Burst Measurement by Flow Cytometry in Neutrophils: A Study of Two Isolation Techniques and Two Bacterial Strains
Ali Osman Gürol
Neutrophils are the most abundant cells, accounting for 50-70% of all white blood cells. They are critical in the immune response against bacterial and fungal pathogens. They are characterized by their ability to rapidly migrate to sites of infection or injury to eliminate invading pathogens. Neutrophils trigger microbicidal mechanisms (...)
and others
Fc Receptor-Like 3 Gene Polymorphism and the Risk of Lupus Nephritis in Systemic Lupus Erythematosus Patients
Mona Sallam Embarek Mohamed
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that affects multiple organs. Its prevalence is higher in women, but its course is more critical in men with bad prognosis expeditious. The exact etiology (...)
and others
Soluble HLA-G as a Novel Biomarker for the Diagnosis of Acute Lymphoblastic Leukemia
Rojan G.M. Al-Allaff
and Sura M.Y. Al-Taee
Acute lymphoblastic leukemia (ALL) is an uncontrolled proliferation of immature lymphocytes that are precursors to either B-cells or T-cells, and their rapid proliferation leads to their collection in the blood, bone marrow, and other organs. ALL is one of the most common (...)
Commentary
Symbiotic Life is a Success of Immunity
Şefik Ş. Alkan
Not so long ago, a tiny virus has turned our lives upside down. We witnessed how our civilization can fall to its knees so easily. After infecting 770 million individuals and killing over 7 million people across the globe, COVID-19 is still with us. Previously, I shortly (...)