CURRENT ISSUE

Function/Left-01
VOLUME 13 Issue 1 April 2025
Editorial
Günnur Deniz
Dear Colleagues, It is our great pleasure to present the first issue of the Turkish Journal of Immunology for 2025. This issue highlights the diversity and depth of current immunological research. In our Review Article, the emerging concept of PANoptosis is explored as a novel form of programmed (...)
Review Article
Mert Karaca and Haluk Barbaros Oral
Programmed cell death (PCD) mechanisms are an inherent part of protection against pathogens and cellular stress. Pyroptosis, apoptosis, and necroptosis are the best-known PCD pathways that protect the body against both internal and external risk factors. The observation that all three cell death pathways can be activated in response to certain stimuli, such as influenza virus (IAV) infection, has raised the question of whether they are triggered independently or work in (...)
Original Research
Mahmoud Mohamed Bahgat

and others

Due to feasibility, small size, easiness of handling and maintaining in an animal house, uncomplicated ethical approval to work with, and a high degree of homology to both the human genome and metabolome (...)
Ali Osman Gürol

and others

Neutrophils are the most abundant cells, accounting for 50-70% of all white blood cells. They are critical in the immune response against bacterial and fungal pathogens. They are characterized by their ability to rapidly migrate to sites of infection or injury to eliminate invading pathogens. Neutrophils trigger microbicidal mechanisms (...)
Mona Sallam Embarek Mohamed

and others

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that affects multiple organs. Its prevalence is higher in women, but its course is more critical in men with bad prognosis expeditious. The exact etiology (...)
Rojan G.M. Al-Allaff and Sura M.Y. Al-Taee
Acute lymphoblastic leukemia (ALL) is an uncontrolled proliferation of immature lymphocytes that are precursors to either B-cells or T-cells, and their rapid proliferation leads to their collection in the blood, bone marrow, and other organs. ALL is one of the most common (...)
Commentary
Şefik Ş. Alkan
Not so long ago, a tiny virus has turned our lives upside down. We witnessed how our civilization can fall to its knees so easily. After infecting 770 million individuals and killing over 7 million people across the globe, COVID-19 is still with us. Previously, I shortly (...)