Turk J Immunol. 2023; 11(2): 42-50 | DOI: 10.4274/tji.galenos.2023.81894

Ayurveda and Allopathic Therapeutic Strategies in Immune Thrombocytopenic Purpura: An Overview

Sayali Rajendra Kale, Pallavi Abhijit Patil
Department of Pharmacology, Bharati Vidyapeeth’s College of Pharmacy, C.B.D. Belapur, Navi Mumbai, Maharashtra, India

Idiopathic thrombocytopenic purpura (ITP) is characterized by immunologic destruction of platelets and normal/enlarged megakaryocytes in the bone marrow. ITP is broken down into acute and chronic variants. Acute forms cause significant bleeding, whereas chronic forms develop slowly and exhibit minimal to no symptoms. Body makes antibodies that are directed against its own platelets, which can lead to internal bleeding, thrombocytopenic purpura, and petechiae. Immunosuppressants, thrombopoietin receptor agonists, corticosteroids, intravenous immunoglobulins, anti-D immunoglobulin, rituximab, and splenectomy are among the treatments for chronic ITP. Around two thirds of patients benefit from existing treatments; however, some sufferers are resistant to them or do not respond to them over the long term. According to Ayurveda scriptures, ITP is related to Tiryaga Raktapitta because all of the Doshas are vitiated, flowing in the blood and manifesting subcutaneously.

Keywords: Immune thrombocytopenic purpura, idiopathic thrombocytopenic purpura, itp, tiryaga raktapitta, platelets, petechiae, autoimmune illness

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