Turk J Immunol. 2020; 8(2): 89-93 | DOI: 10.25002/tji.2020.1260

Immunological Manifestations of Helicobacter pylori Infection: Polyserositis?

Tiago Borges¹, Arsenio Barbaso², Sergio Silva^1
1Trofa Saúde Hospital Privado em Gaia, Department of Internal Medicine, Vila Nova de Gaia, Portugal
²Centro Hospitalar Universitário de São João, Department of Internal Medicine, Porto, Portugal

Polyserositis is the general inflammation of serous membranes with associated effusion. Except for tuberculosis and coxsackie virus, infections are a very rare cause of polyserositis. We describe a case of a 41-year-old woman with chronic mild thrombocytopenia that presented with polyserositis and whose investigation was negative for common causes of serosal inflammation, showing great clinical improvement after Helicobacter pylori eradication therapy. Besides serositis, we also discuss other immunological manifestations of Helicobacter pylori infection. To our knowledge, this is the first case that establishes Helicobacter pylori as a potential cause of serosal inflammation, thus expanding immunological manifestations of Helicobacter pylori infection.

Keywords: Helicobacter pylori, serositis, thrombocytopenia

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Helicobacter pylori Ýnfeksiyonunda Baðýþýklýk Yanýtý: Poliserozit

Tiago Borges¹, Arsenio Barbaso², Sergio Silva^1
1Trofa Saúde Hospital Privado em Gaia, Department of Internal Medicine, Vila Nova de Gaia, Portugal
²Centro Hospitalar Universitário de São João, Department of Internal Medicine, Porto, Portugal

Poliserozit seröz membranlara karþý oluþan genel yangý ile birlikte oluþan efüzyondur. Bu olgu sunumunda bir serozal yangý nedeni bulunmayan, ýlýmlý kronik trombositopenisi olan 41 yaþýndaki kadýn hastada geliþen poliserozitin, var olan Helicobacter pylori enfeksiyonunun tedavisinden sonra tam bir klinik iyileþme gösteren vaka sunuldu. Bu sunumda, serozit dýþýnda, Helicobacter pylori enfeksiyonunun baðýþýklýk sistemindeki etkileri de tartýþýldý. Bu olgu sunumu, bilgilerimize göre, Helicobacter pylori enfeksiyonunun neden olduðu gösterilen ilk serozaya karþý yangý makalesidir ve buradaki bulgular Helicobacter pylori enfeksiyonunun baðýþýklýk sisteminde meydana getirdikleri ile ilgili bilgilerimizi artýrmaktadýr.

Anahtar Kelimeler: Helicobacter pylori, serozit, trombositopeni

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