Dear Colleagues,

It is our great pleasure to present the first issue of the Turkish Journal of Immunology for 2025.

This issue highlights the diversity and depth of current immunological research. In our Review Article, the emerging concept of PANoptosis is explored as a novel form of programmed cell death, shedding light on its intricate relationship with immune responses and inflammatory diseases.

Our Original Research Articles span various themes across experimental and clinical immunology. A murine study investigates how genetic background and gender influence susceptibility to H1N1 infection, underlining the complexity of host immune responses. Another contribution identifies soluble HLA-G as a promising biomarker for the diagnosis of acute lymphoblastic leukemia, while a third paper examines Fc receptor-like-3 gene polymorphisms in lupus nephritis patients, providing insight into genetic risk factors in autoimmunity. A final research article presents a methodological comparison of oxidative burst assays in neutrophils, offering practical guidance for laboratory immunologists working with flow cytometry.

The issue concludes with a Commentary titled "Symbiotic Life is a Success of Immunity," which reflects on the evolutionary interplay between host and microorganisms and emphasizes the immunological foundations of life’s symbiotic balance.

We thank our authors, reviewers, and editorial board members for their continued commitment to scientific excellence. This issue marks not only the beginning of a new volume but also a fresh chapter for our journal as we transition to a new publishing platform. With DOC Design and Informatics as our new publisher, we aim to further elevate the visibility and impact of TJI within the international immunology community. 

We warmly invite you to submit your research to the Turkish Journal of Immunology. With your valuable contributions and support, our journal will continue to grow stronger.

With warm regards,
Prof. Günnur Deniz
On behalf of the Editorial Board
Turkish Journal of Immunology